About: Male gender and kidney illness associated with an increased risk of severe laboratory-confirmed coronavirus disease

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Male gender and kidney illness associated with an increased risk of severe laboratory-confirmed coronavirus disease
Creator	Murillo-Zamora, Efrén
source	MedRxiv
abstract	Objective: To identify factors predicting severe coronavirus disease 2019 (COVID-19) in adolescent and adult patients with laboratory-positive (quantitative reverse-transcription polymerase chain reaction) infection. Methods: A retrospective cohort study took place, and data from 740 subjects, from all 32 states of Mexico, were analyzed. The association between the studied factors and severe (dyspnea requiring hospital admission) COVID-19 was evaluated through risk ratios (RRs) and 95% confidence intervals (CIs). Results: Severe illness was documented in 28% of participants. In multiple analysis, male gender (RR = 1.13, 95% CI 1.06 - 1.20), advanced age ([reference: 15 - 29 years old] 30 - 44, RR = 1.02, 95% CI 0.94 - 1.11; 45 - 59, RR = 1.26, 95% CI 1.15 - 1.38; 60 years or older, RR = 1.44, 95% CI 1.29 - 1.60), chronic kidney disease (RR = 1.31, 95% CI 1.04 - 1.64) and thoracic pain (RR = 1.16, 95% CI 1.10 - 1.24) were associated with an increased risk of severe disease. Conclusions: To the best of our knowledge, this is the first study evaluating predictors of COVID-19 severity in a large subset of the Latin-American population. It is also the first in documenting gender-related differences regarding the severity of the illness. These results may be useful for health care protocols for the early detection and management of COVID-19 patients that may benefit from opportune and specialized supportive medical treatment.
has issue date	2020-07-01(xsd:dateTime)
bibo:doi	10.1101/2020.06.29.20142562
has license	medrxiv
sha1sum (hex)	faf4184c1c35dcb4d7634b97f77f5378500c9fd3
schema:url	https://doi.org/10.1101/2020.06.29.20142562
resource representing a document's title	Male gender and kidney illness associated with an increased risk of severe laboratory-confirmed coronavirus disease
resource representing a document's body	covid:faf4184c1c35dcb4d7634b97f77f5378500c9fd3#body_text
is schema:about of	named entity 'coronavirus' named entity 'illness' named entity 'coronavirus disease' named entity 'kidney' named entity 'coronavirus disease' »more»

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