About: Sensitive Commercial NASBA Assay for the Detection of Respiratory Syncytial Virus in Clinical Specimen

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About: Sensitive Commercial NASBA Assay for the Detection of Respiratory Syncytial Virus in Clinical Specimen Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Sensitive Commercial NASBA Assay for the Detection of Respiratory Syncytial Virus in Clinical Specimen
Creator	Schildgen, O Simon, A Tillmann, R Mü Ller, A
source	Medline; PMC
abstract	The aim of the study was to evaluate the usability of three diagnostic procedures for the detection of respiratory syncytial virus in clinical samples. Therefore, the FDA cleared CE marked NOW® RSV ELISA, the NucliSENS® EasyQ RSV A+B NASBA, and a literature based inhouse RT-PCR protocol were compared for their relative sensitivities. Thereby, NASBA turned out to be the most sensitive method with a total number of 80 RSV positive samples out of a cohort of 251 nasopharyngeal washings from patients suffering from clinical symptoms, followed by the inhouse RT-PCR (62/251) and ELISA (52/251). Thus, NASBA may serve as a rapid and highly sensitive alternative for RSV diagnostics.
has issue date	2007-12-26(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0001357
bibo:pmid	18159240
has license	cc-by
sha1sum (hex)	f73805f1ce75d2478a2c127a20008ab0a986f043
schema:url	https://doi.org/10.1371/journal.pone.0001357
resource representing a document's title	Sensitive Commercial NASBA Assay for the Detection of Respiratory Syncytial Virus in Clinical Specimen
has PubMed Central identifier	PMC2137935
has PubMed identifier	18159240
schema:publication	PLoS One
resource representing a document's body	covid:f73805f1ce75d2478a2c127a20008ab0a986f043#body_text
is schema:about of	named entity 'aim' named entity 'Specimen' named entity 'RT-PCR' named entity 'DIAGNOSTICS' named entity 'THEIR' »more»

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