About: COVID-19 impact on consecutive neurological patients admitted to the emergency department

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	COVID-19 impact on consecutive neurological patients admitted to the emergency department
Creator	Filosto, Massimiliano Alberici, Antonella Baldelli, Enrico Benini, Matteo Benussi, Alberto »more»
source	MedRxiv
abstract	Abstract Objective: Aim of this study was to analyse the impact of COVID-19 on clinical and laboratory findings and outcome of neurological patients consecutively admitted to the emergency department (ED) of a tertiary hub center. Methods: All adult patients consecutively admitted to the ED for neurological manifestations from February 20 th through April 30 th 2020 at Spedali Civili of Brescia entered the study. Demographic, clinical, and laboratory data were extracted from medical records and compared between patients with and without COVID-19. Results: Out of 505 consecutively patients evaluated at ED with neurological symptoms, 147 (29.1%) tested positive for SARS-CoV-2. These patients displayed at triage higher values of CRP, AST, ALT, and fibrinogen but not lymphopenia (p<0.05). They were older (73.1 + 12.4 vs 65.1 + 18.9 years, p=0.001) had higher frequency of stroke (34.7% vs 29.3%), encephalitis/meningitis (9.5% vs 1.9%) and delirium (16.3% vs 5.0%). Compared to patients without COVID, they were more frequently hospitalized (91.2% vs 69.3%, p<0.0001) and showed higher mortality rates (29.7% vs 1.8%, p<0.0.001) and discharge disability, independently from age. Conclusions: COVID-19 impacts on clinical presentation of neurological disorders, with higher frequency of stroke, encephalitis and delirium, and was strongly associated with increased hospitalisation, mortality and disability.
has issue date	2020-05-26(xsd:dateTime)
bibo:doi	10.1101/2020.05.23.20110650
has license	medrxiv
sha1sum (hex)	f6b4cc9c0fed7fd0b62e74890704892045e21b8b
schema:url	https://doi.org/10.1101/2020.05.23.20110650
resource representing a document's title	COVID-19 impact on consecutive neurological patients admitted to the emergency department
resource representing a document's body	covid:f6b4cc9c0fed7fd0b62e74890704892045e21b8b#body_text
is schema:about of	named entity 'medical records' named entity 'manifestations' named entity 'laboratory' named entity 'neurological' named entity 'emergency department' »more»

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