About: The impact of super-spreaders in COVID-19: mapping genome variation worldwide

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The impact of super-spreaders in COVID-19: mapping genome variation worldwide Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	The impact of super-spreaders in COVID-19: mapping genome variation worldwide
Creator	Martinón-Torres, Federico Gómez-Carballa, Alberto Pardo-Seco, Jacobo Salas, Antonio Bello, Xabier
source	BioRxiv
abstract	The human pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the major pandemic of the 21st century. We analyzed >4,700 SARS-CoV-2 genomes and associated meta-data retrieved from public repositories. SARS-CoV-2 sequences have a high sequence identity (>99.9%), which drops to >96% when compared to bat coronavirus. We built a mutation-annotated reference SARS-CoV-2 phylogeny with two main macro-haplogroups, A and B, both of Asian origin, and >160 sub-branches representing virus strains of variable geographical origins worldwide, revealing a uniform mutation occurrence along branches that could complicate the design of future vaccines. The root of SARS-CoV-2 genomes locates at the Chinese haplogroup B1, with a TMRCA dating to 12 November 2019 - thus matching epidemiological records. Sub-haplogroup A2a originates in China and represents the major non-Asian outbreak. Multiple founder effect episodes, most likely associated with super-spreader hosts, explain COVID-19 pandemic to a large extent.
has issue date	2020-06-12(xsd:dateTime)
bibo:doi	10.1101/2020.05.19.097410
has license	biorxiv
sha1sum (hex)	f1ca6eb80ab85482a58e4322b5980a2408687984
schema:url	https://doi.org/10.1101/2020.05.19.097410
resource representing a document's title	The impact of super-spreaders in COVID-19: mapping genome variation worldwide
schema:publication	bioRxiv
resource representing a document's body	covid:f1ca6eb80ab85482a58e4322b5980a2408687984#body_text
is schema:about of	named entity 'revealing' named entity 'responsible' named entity 'Multiple' named entity 'human pathogen' named entity 'Asian' »more»

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software