About: Monitoring antibody response following SARS-CoV-2 infection: Diagnostic efficiency of four automated immunoassays

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About: Monitoring antibody response following SARS-CoV-2 infection: Diagnostic efficiency of four automated immunoassays Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Monitoring antibody response following SARS-CoV-2 infection: Diagnostic efficiency of four automated immunoassays
Creator	Dahma, Hafid Vandenberg, Olivier Montesinos, Isabel Van Den Wijngaert, Sigi Cotton, Frédéric »more»
source	Elsevier; Medline; PMC
abstract	INTRODUCTION: SARS-CoV-2 seroconversion is important for epidemiological studies as well as contact tracing. MATERIAL AND METHODS: The antibody response against SARS-CoV-2 was examined in 111 patients with a positive qRT-PCR. Seroconversion was assessed using the Elecsys from Roche, the Liaison S1/S2 IgG from Diasorin, the IgG and IgA from Euroimmun as well as the VIDAS IgG and IgM. Specificity was estimated based on the measurement of SARS-CoV-2 antibodies in 96 residual samples collected during a non-pandemic period. RESULTS: The highest overall sensitivity for detecting seroconversion was obtained using the Elecsys (81.1%), the Euroimmun with a combined detection of IgG/IgA (86.5%) and the VIDAS with a simultaneous measurement of IgG/IgM (78.4%).The Elecsys and the VIDAS IgG/IgM demonstrated a specificity as well as a positive predictive value of 100%. CONCLUSIONS: The Elecsys and the VIDAS methods with a combination of IgG/IgM measurement demonstrated a high sensitivity with no false positive results.
has issue date	2020-07-12(xsd:dateTime)
bibo:doi	10.1016/j.diagmicrobio.2020.115140
bibo:pmid	32829098
has license	no-cc
sha1sum (hex)	ed19765f5db57e8b849e73f9f9c82bda9f6f1be7
schema:url	https://doi.org/10.1016/j.diagmicrobio.2020.115140
resource representing a document's title	Monitoring antibody response following SARS-CoV-2 infection: Diagnostic efficiency of four automated immunoassays
has PubMed Central identifier	PMC7354376
has PubMed identifier	32829098
schema:publication	Diagn Microbiol Infect Dis
resource representing a document's body	covid:ed19765f5db57e8b849e73f9f9c82bda9f6f1be7#body_text
is schema:about of	named entity 'COI' named entity 'specificity' named entity 'qRT-PCR' named entity 'samples' named entity 'Word count' »more»

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