About: Are pangolins the intermediate host of the 2019 novel coronavirus (SARS-CoV-2)?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Are pangolins the intermediate host of the 2019 novel coronavirus (SARS-CoV-2)?
Creator	Chen, Jing Liu, Ping Hou, Fanghui Hua, Yan Wang, Xiaohu »more»
source	Medline; PMC
abstract	The outbreak of a novel corona Virus Disease 2019 (COVID-19) in the city of Wuhan, China has resulted in more than 1.7 million laboratory confirmed cases all over the world. Recent studies showed that SARS-CoV-2 was likely originated from bats, but its intermediate hosts are still largely unknown. In this study, we assembled the complete genome of a coronavirus identified in 3 sick Malayan pangolins. The molecular and phylogenetic analyses showed that this pangolin coronavirus (pangolin-CoV-2020) is genetically related to the SARS-CoV-2 as well as a group of bat coronaviruses but do not support the SARS-CoV-2 emerged directly from the pangolin-CoV-2020. Our study suggests that pangolins are natural hosts of Betacoronaviruses. Large surveillance of coronaviruses in pangolins could improve our understanding of the spectrum of coronaviruses in pangolins. In addition to conservation of wildlife, minimizing the exposures of humans to wildlife will be important to reduce the spillover risks of coronaviruses from wild animals to humans.
has issue date	2020-05-14(xsd:dateTime)
bibo:doi	10.1371/journal.ppat.1008421
bibo:pmid	32407364
has license	cc-by
sha1sum (hex)	eb9c94c70b4e601fbb0b3427f661262ee2f61bed
schema:url	https://doi.org/10.1371/journal.ppat.1008421
resource representing a document's title	Are pangolins the intermediate host of the 2019 novel coronavirus (SARS-CoV-2)?
has PubMed Central identifier	PMC7224457
has PubMed identifier	32407364
schema:publication	PLoS Pathog
resource representing a document's body	covid:eb9c94c70b4e601fbb0b3427f661262ee2f61bed#body_text
is schema:about of	named entity 'SUPPORT' named entity 'THE CITY' named entity 'STUDY' named entity '1.7' named entity 'OUTBREAK' »more»

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