About: Incidence of Gastrointestinal Stromal Tumor: A Retrospective Study Based on Immunohistochemical and Mutational Analyses

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About: Incidence of Gastrointestinal Stromal Tumor: A Retrospective Study Based on Immunohistochemical and Mutational Analyses Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Incidence of Gastrointestinal Stromal Tumor: A Retrospective Study Based on Immunohistochemical and Mutational Analyses
Creator	Huang, Y.-J Huang, Ying-Jie Lai, G.-L Lai, Guan-Lin Lin, P.-C »more»
source	Medline; PMC
abstract	The aim of this study is to estimate the incidence of the gastrointestinal stromal tumor after the previous diagnoses were confirmed and/or revised by both immunohistochemical and mutational analyses. We reviewed 17,858 surgically excised gastrointestinal lesions in our hospital from 1998 to 2004. All mesenchymal tumors were examined for CD117 expression by immunohistochemistry, and every CD117-negative mesenchymal tumors were further subjected to mutational analysis for KIT and PDGFRA exons. The results showed that approximately 35% of gastrointestinal stromal tumors were misdiagnosed if immunohistochemical analysis of CD117 expression was not performed; and approximately 15% misdiagnosed if mutation analysis was not available. Because approximately 4.72% of patients with gastrointestinal malignancies in Taiwan were treated in our hospital and the average of newly diagnosed gastrointestinal stromal tumors in our hospital was 14.33 cases per year, the estimated annual incidents of gastrointestinal stromal tumor in Taiwan were 303.60. Therefore, the annual incidence of gastrointestinal stromal tumor is 13.74 per million Taiwanese.
has issue date	2007-01-26(xsd:dateTime)
bibo:doi	10.1007/s10620-006-9480-y
bibo:pmid	17253141
has license	no-cc
sha1sum (hex)	de56bf4d5d5239ed9213f65751844a3c3204edce
schema:url	https://doi.org/10.1007/s10620-006-9480-y
resource representing a document's title	Incidence of Gastrointestinal Stromal Tumor: A Retrospective Study Based on Immunohistochemical and Mutational Analyses
has PubMed Central identifier	PMC7087581
has PubMed identifier	17253141
schema:publication	Dig Dis Sci
resource representing a document's body	covid:de56bf4d5d5239ed9213f65751844a3c3204edce#body_text
is schema:about of	named entity 'mutational' named entity 'LESIONS' named entity 'EXAMINED FOR' named entity 'MUTATIONAL ANALYSIS' named entity 'REVIEWED' »more»

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