About: Femtomolar-level detection of SARS-CoV-2 spike proteins using toroidal plasmonic metasensors

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Femtomolar-level detection of SARS-CoV-2 spike proteins using toroidal plasmonic metasensors Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Femtomolar-level detection of SARS-CoV-2 spike proteins using toroidal plasmonic metasensors
Creator	Kaushik, Ajeet Ahmadivand, Arash Gerislioglu, Burak Ghoreishi, S Manickam, Pandiaraj »more»
source	ArXiv
abstract	Effective and efficient management of human betacoronavirus severe acute respiratory syndrome (SARS)-CoV-2 infection i.e., COVID-19 pandemic, required sensitive sensors with short sample-to-result durations for performing diagnostics. In this direction, one of appropriate alternative approach to detect SARS-CoV-2 at low level (fmol) is exploring plasmonic metasensor technology for COVID-19 diagnostics, which offers exquisite opportunities in advanced healthcare programs, and modern clinical diagnostics. The intrinsic merits of plasmonic metasensors stem from their capability to squeeze electromagnetic fields, simultaneously in frequency, time, and space. However, the detection of low-molecular weight biomolecules at low densities is a typical drawback of conventional metasensors that has recently been addressed using toroidal metasurface technology. This research reports fabrication of a miniaturized plasmonic immunosensor based on toroidal electrodynamics concept that can sustain robustly confined plasmonic modes with ultranarrow lineshapes in the terahertz (THz) frequencies. By exciting toroidal dipole mode using our quasi-infinite metasurface and a judiciously optimized protocol based on functionalized gold nanoparticles (NPs) conjugated with the specific monoclonal antibody of SARS-CoV-2 onto the metasurface, the resonance shifts for diverse concentrations of the spike protein is monitored. Possessing molecular weight around ~76 kDa allowed us to detect the presence of spike protein with significantly low LoD ~4.2 fmol.
has issue date	2020-06-15(xsd:dateTime)
has license	arxiv
sha1sum (hex)	d4b620d322062b8277d47fbce4828d597758c21e
resource representing a document's title	Femtomolar-level detection of SARS-CoV-2 spike proteins using toroidal plasmonic metasensors
resource representing a document's body	covid:d4b620d322062b8277d47fbce4828d597758c21e#body_text
is schema:about of	named entity 'However' named entity 'technology' named entity 'sustain' named entity 'short' named entity 'THEIR' »more»

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software