About: Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak

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About: Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak
Creator	Kageyama, Tsutomu Nao, Naganori Saito, Shinji Takayama, Ikuyo Wakita, Takaji »more»
source	MedRxiv
abstract	The Diamond Princess (DP) cruise ship was put under quarantine offshore Yokohama, Japan, after a passenger who disembarked in Hong Kong was confirmed as a COVID-19 case. We performed whole genome sequencing of SARS-CoV-2 directly from PCR-positive clinical specimens and conducted a haplotype network analysis of the outbreak. All tested isolates exhibited a transversion at G11083T, suggesting that SARS-CoV-2 dissemination on the DP originated from a single introduction event before the quarantine started. Although further spreading might have been prevented by quarantine, some progeny clusters were linked to transmission through mass-gathering events in the recreational areas and direct transmission among passengers who shared cabins during the quarantine. This study demonstrates the usefulness of haplotype network analysis in identifying potential infection routes.
has issue date	2020-03-27(xsd:dateTime)
bibo:doi	10.1101/2020.03.23.20041970
has license	medrxiv
sha1sum (hex)	d28ef2265d20d11e5df19330a761f297059fa38f
schema:url	https://doi.org/10.1101/2020.03.23.20041970
resource representing a document's title	Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak
resource representing a document's body	covid:d28ef2265d20d11e5df19330a761f297059fa38f#body_text
is schema:about of	named entity 'Haplotype' named entity 'Haplotype' named entity 'genome' named entity 'SNVs' named entity 'hydrolytic' »more»

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