About: Nosocomial viral ventilator-associated pneumonia in the intensive care unit: a prospective cohort study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Nosocomial viral ventilator-associated pneumonia in the intensive care unit: a prospective cohort study
Creator	Freymuth, François Vabret, Astrid Charbonneau, Pierre Parienti, Jean-Jacques Ramakers, Michel »more»
source	Medline; PMC
abstract	OBJECTIVE: To determine the incidence, risk factors, and clinical relevance of viral ventilator-associated pneumonia (VAP) in an adult intensive care unit (ICU). DESIGN: Prospective observational study. SETTING: A 22-bed adult medical ICU in a university hospital. PATIENTS: All consecutive adult patients ventilated more than 48 h in a 9-month period including regular seasonal viral infections. INTERVENTIONS: A tracheobronchial aspirate upon enrollment and at the time of VAP suspicion. MEASUREMENTS AND RESULTS: All respiratory specimens were tested in culture, indirect immunofluorescence assay, and PCR or RT-PCR for virological assessment. Patients were followed until ICU discharge or death. One hundred thirty-nine patients were included. Upon enrollment, a respiratory virus was detected in the tracheobronchial aspirate in 25% of patients (35 of 139). The incidence of VAP, defined according to clinical daily evaluation, was 28% (39 of 139 patients). A bacteria was documented in 74% of cases, whereas no case of a causative viral infection was encountered among VAP patients; however, herpes simplex virus type-1 (HSV 1) infection was detected in respiratory specimens of 31% of VAP (12 of 39). CONCLUSIONS: We found a high incidence of HSV-1 infection in VAP patients; however, nosocomial viral VAP is likely to be rare in ICU, as assessed by the absence of respiratory virus-induced VAP identified in this prospective cohort study.
has issue date	2005-07-06(xsd:dateTime)
bibo:doi	10.1007/s00134-005-2706-1
bibo:pmid	15999253
has license	no-cc
sha1sum (hex)	c68f8c6cb48f02e98cc75e94ed64b96561971457
schema:url	https://doi.org/10.1007/s00134-005-2706-1
resource representing a document's title	Nosocomial viral ventilator-associated pneumonia in the intensive care unit: a prospective cohort study
has PubMed Central identifier	PMC7079837
has PubMed identifier	15999253
schema:publication	Intensive Care Med
resource representing a document's body	covid:c68f8c6cb48f02e98cc75e94ed64b96561971457#body_text
is schema:about of	named entity 'Design' named entity 'cases' named entity 'viral infection' named entity 'specimens' named entity 'VAP' »more»

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