About: Human core duplicon gene families: game changers or game players?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Human core duplicon gene families: game changers or game players?
Creator	Bekpen, Cemalettin Tautz, Diethard
source	PMC
abstract	Illuminating the role of specific gene duplications within the human lineage can provide insights into human-specific adaptations. The so-called human core duplicon gene families have received particular attention in this respect, due to special features, such as expansion along single chromosomes, newly acquired protein domains and signatures of positive selection. Here, we summarize the data available for 10 such families and include some new analyses. A picture emerges that suggests broad functions for these protein families, possibly through modification of core cellular pathways. Still, more dedicated studies are required to elucidate the function of core-duplicons gene families and how they have shaped adaptations and evolution of humans.
has issue date	2019-09-16(xsd:dateTime)
bibo:doi	10.1093/bfgp/elz016
bibo:pmid	31529038
has license	cc-by
sha1sum (hex)	c1e2ffff403bab75c973812b3bf2e8d5a2f07600
schema:url	https://doi.org/10.1093/bfgp/elz016
resource representing a document's title	Human core duplicon gene families: game changers or game players?
has PubMed Central identifier	PMC6920530
has PubMed identifier	31529038
schema:publication	Brief Funct Genomics
resource representing a document's body	covid:c1e2ffff403bab75c973812b3bf2e8d5a2f07600#body_text
is schema:about of	named entity 'data' named entity 'Illuminating' named entity 'attention' named entity 'game' named entity 'GAME' »more»

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