About: Alternative Methods of Vaccine Delivery: An Overview of Edible and Intradermal Vaccines

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About: Alternative Methods of Vaccine Delivery: An Overview of Edible and Intradermal Vaccines Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Alternative Methods of Vaccine Delivery: An Overview of Edible and Intradermal Vaccines
Creator	Clementi, N Caputo, V Criscuolo, E Diotti, R Kirchenbaum, G »more»
source	Medline; PMC
abstract	Vaccines are recognized worldwide as one of the most important tools for combating infectious diseases. Despite the tremendous value conferred by currently available vaccines toward public health, the implementation of additional vaccine platforms is also of key importance. In fact, currently available vaccines possess shortcomings, such as inefficient triggering of a cell-mediated immune response and the lack of protective mucosal immunity. In this regard, recent work has been focused on vaccine delivery systems, as an alternative to injectable vaccines, to increase antigen stability and improve overall immunogenicity. In particular, novel strategies based on edible or intradermal vaccine formulations have been demonstrated to trigger both a systemic and mucosal immune response. These novel vaccination delivery systems offer several advantages over the injectable preparations including self-administration, reduced cost, stability, and elimination of a cold chain. In this review, the latest findings and accomplishments regarding edible and intradermal vaccines are described in the context of the system used for immunogen expression, their molecular features and capacity to induce a protective systemic and mucosal response.
has issue date	2019-03-04(xsd:dateTime)
bibo:doi	10.1155/2019/8303648
bibo:pmid	30949518
has license	cc-by
sha1sum (hex)	c07b96b0ac94d1403d44dff3bc6ad12a64d171c1
schema:url	https://doi.org/10.1155/2019/8303648
resource representing a document's title	Alternative Methods of Vaccine Delivery: An Overview of Edible and Intradermal Vaccines
has PubMed Central identifier	PMC6425294
has PubMed identifier	30949518
schema:publication	J Immunol Res
resource representing a document's body	covid:c07b96b0ac94d1403d44dff3bc6ad12a64d171c1#body_text
is schema:about of	named entity 'VACCINE DELIVERY' named entity 'METHODS' named entity 'immunity' named entity 'Alternative Methods' named entity 'VACCINES' »more»

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