About: Infectious complications after allogeneic stem cell transplantation: epidemiology and interventional therapy strategies: Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)

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About: Infectious complications after allogeneic stem cell transplantation: epidemiology and interventional therapy strategies: Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Infectious complications after allogeneic stem cell transplantation: epidemiology and interventional therapy strategies: Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
Creator	Klingebiel, Thomas Einsele, Hermann Hebart, Holger Kiehl, Michael Beyer, Jörg »more»
source	PMC
abstract	The risk of infection after allogeneic stem cell transplantation is determined by the underlying disease, the intensity of previous treatments and complications that may have occurred during that time, but above all, the risk of infection is determined by the selected transplantation modality (e.g. HLA-match between the stem cell donor and recipient, T cell depletion of the graft, and others). In comparison with patients treated with high-dose chemotherapy and autologous stem cell transplantation, patients undergoing allogeneic stem cell transplantation are at a much higher risk of infection even after hematopoietic reconstitution, due to the delayed recovery of T and B cell functions. The rate at which immune function recovers after hematopoietic reconstitution greatly influences the incidence and type of post-transplant infectious complications. Infection-associated mortality, for example, is significantly higher following engraftment than during the short neutropenic period that immediately follows transplantation.
has issue date	2003-09-10(xsd:dateTime)
bibo:doi	10.1007/s00277-003-0772-4
bibo:pmid	13680165
has license	no-cc
sha1sum (hex)	be6f35c7e060adccbd8b68fd8a0439c8877e4443
schema:url	https://doi.org/10.1007/s00277-003-0772-4
resource representing a document's title	Infectious complications after allogeneic stem cell transplantation: epidemiology and interventional therapy strategies: Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
has PubMed Central identifier	PMC7103165
has PubMed identifier	13680165
schema:publication	Ann Hematol
resource representing a document's body	covid:be6f35c7e060adccbd8b68fd8a0439c8877e4443#body_text
is schema:about of	named entity 'determined' named entity 'infection' named entity 'patients' named entity 'chemotherapy' named entity 'recovery' »more»

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