About: Commensal bacteria as a novel delivery system for subunit vaccines directed against agents of bioterrorism

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About: Commensal bacteria as a novel delivery system for subunit vaccines directed against agents of bioterrorism Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Commensal bacteria as a novel delivery system for subunit vaccines directed against agents of bioterrorism
Creator	Hruby, Dennis Wilson, Rebecca
source	Elsevier; Medline; PMC
abstract	Abstract Following the anthrax attacks of 2001 and the recent SARS outbreak, concerns about emerging and re-emerging infectious diseases have catalyzed a renewed interest in developing new vaccination strategies that provide rapid and flexible response options to future threats. Because the probability of encountering one of these exotic agents is unknown, it is essential that new vaccine formulations employ methods that provide effective protection and extremely good safety profiles if they are to be used by either military or civilian populations. One approach, which potentially satisfies these criteria, is the use of live recombinant Gram-positive commensal bacteria as expression vectors. This review provides an overview of the system, its advantages and limitations, and details an example of how Gram-positive commensal bacteria are being developed as a fifth generation vaccine against a Class A biowarfare pathogen, namely smallpox.
has issue date	2005-06-17(xsd:dateTime)
bibo:doi	10.1016/j.addr.2005.01.015
bibo:pmid	15935879
has license	els-covid
sha1sum (hex)	bcde15209d8d14135e73cdf3f208401dd6ded3be
schema:url	https://doi.org/10.1016/j.addr.2005.01.015
resource representing a document's title	Commensal bacteria as a novel delivery system for subunit vaccines directed against agents of bioterrorism
has PubMed Central identifier	PMC7125890
has PubMed identifier	15935879
schema:publication	Advanced Drug Delivery Reviews
resource representing a document's body	covid:bcde15209d8d14135e73cdf3f208401dd6ded3be#body_text
is schema:about of	named entity 'NOVEL' named entity 'future' named entity 'Following' named entity 'advantages' named entity 'system' »more»

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