About: Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study
Creator	Acker, Karen Brandler, Michael Cangemi, Carla Delamora, Patricia Dipace, Jennifer »more»
source	Elsevier; Medline; PMC
abstract	BACKGROUND: The risk of vertical and perinatal transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, which causes COVID-19), the most appropriate management, and the neonate's risk of developing COVID-19 during the perinatal period are unknown. Therefore, we aimed to elucidate best practices regarding infection control in mother–newborn dyads, and identify potential risk factors associated with transmission. METHODS: In this observational cohort study, we identified all neonates born between March 22 and May 17, 2020, at three New York Presbyterian Hospitals in New York City (NY, USA) to mothers positive for SARS-CoV-2 at delivery. Mothers could practice skin-to-skin care and breastfeed in the delivery room, but had to wear a surgical mask when near their neonate and practice proper hand hygiene before skin-to-skin contact, breastfeeding, and routine care. Unless medically required, neonates were kept in a closed Giraffe isolette in the same room as their mothers, and were held by mothers for feeding after appropriate hand hygiene, breast cleansing, and placement of a surgical mask. Neonates were tested for SARS-CoV-2 by use of real-time PCR on nasopharyngeal swabs taken at 24 h, 5–7 days, and 14 days of life, and were clinically evaluated by telemedicine at 1 month of age. We recorded demographics, neonatal, and maternal clinical presentation, as well as infection control practices in the hospital and at home. FINDINGS: Of 1481 deliveries, 116 (8%) mothers tested positive for SARS-CoV-2; 120 neonates were identified. All neonates were tested at 24 h of life and none were positive for SARS-CoV-2. 82 (68%) neonates completed follow-up at day 5–7 of life. Of the 82 neonates, 68 (83%) roomed in with the mothers. All mothers were allowed to breastfeed; at 5–7 days of life, 64 (78%) were still breastfeeding. 79 (96%) of 82 neonates had a repeat PCR at 5–7 days of life, which was negative in all; 72 (88%) neonates were also tested at 14 days of life and none were positive. None of the neonates had symptoms of COVID-19. INTERPRETATION: Our data suggest that perinatal transmission of COVID-19 is unlikely to occur if correct hygiene precautions are undertaken, and that allowing neonates to room in with their mothers and direct breastfeeding are safe procedures when paired with effective parental education of infant protective strategies. FUNDING: None.
has issue date	2020-07-23(xsd:dateTime)
bibo:doi	10.1016/s2352-4642(20)30235-2
bibo:pmid	32711687
has license	no-cc
sha1sum (hex)	b34eb4bbbdef99ee3c30e405a887d38a15a68e71
schema:url	https://doi.org/10.1016/s2352-4642%2820%2930235-2
resource representing a document's title	Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study
has PubMed Central identifier	PMC7377726
has PubMed identifier	32711687
schema:publication	Lancet Child Adolesc Health
resource representing a document's body	covid:b34eb4bbbdef99ee3c30e405a887d38a15a68e71#body_text
is schema:about of	named entity 'risk' named entity 'vertical' named entity 'COVID-19' named entity 'COVID-19' named entity 'APPROPRIATE' »more»

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