About: An Outbreak of Fatal Bordetella bronchiseptica Bronchopneumonia in Puppies

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	An Outbreak of Fatal Bordetella bronchiseptica Bronchopneumonia in Puppies
Creator	Uchida, K Chambers, J Haritani, M Matsumoto, I Nakayama, H »more»
source	Elsevier; Medline; PMC
abstract	Summary Twenty-two newborn puppies that did not receive colostrum exhibited acute respiratory signs and died at a breeding facility. Pathological examinations were performed on four of the puppies. At necropsy examination, the lungs were firm and mottled dark red, consistent with acute bronchopneumonia. Histopathologically, there was marked infiltration of neutrophils and macrophages into the bronchi and alveoli, and gram-negative coccobacilli were attached diffusely to the cilia of bronchial mucosa. Immunohistochemistry for Bordetella bronchiseptica antigen revealed positive labelling of the bacterial agents. On electron microscopy, a large number of coccobacilli were observed attaching to the cilia of bronchial epithelial cells. Real-time polymerase chain reaction amplified a B. bronchiseptica gene from the affected lung tissue. Based on these findings, the four puppies were diagnosed with fatal B. bronchiseptica bronchopneumonia.
has issue date	2019-02-28(xsd:dateTime)
bibo:doi	10.1016/j.jcpa.2018.12.002
bibo:pmid	30898296
has license	els-covid
sha1sum (hex)	b09e9b19f23de6ea73d90c3bee402c6cdf680ac3
schema:url	https://doi.org/10.1016/j.jcpa.2018.12.002
resource representing a document's title	An Outbreak of Fatal Bordetella bronchiseptica Bronchopneumonia in Puppies
has PubMed Central identifier	PMC7094580
has PubMed identifier	30898296
schema:publication	Journal of Comparative Pathology
resource representing a document's body	covid:b09e9b19f23de6ea73d90c3bee402c6cdf680ac3#body_text
is schema:about of	named entity 'receive' named entity 'B. bronchiseptica' named entity 'puppies' named entity 'gram-negative' named entity 'Fatal' »more»

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