About: Evaluation of a COVID-19 IgM and IgG rapid test; an efficient tool for assessment of past exposure to SARS-CoV-2

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About: Evaluation of a COVID-19 IgM and IgG rapid test; an efficient tool for assessment of past exposure to SARS-CoV-2 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Evaluation of a COVID-19 IgM and IgG rapid test; an efficient tool for assessment of past exposure to SARS-CoV-2
Creator	Lundkvist, Åke Rönnberg, Bengt Akaberi, Dario Esmaeilzadeh, Mouna Hoffman, Tove »more»
source	Medline; PMC
abstract	COVID-19 is the most rapidly growing pandemic in modern time, and the need for serological testing is most urgent. Although the diagnostics of acute patients by RT-PCR is both efficient and specific, we are also crucially in need of serological tools for investigating antibody responses and assessing individual and potential herd immunity. We evaluated a commercially available test developed for rapid (within 15 minutes) detection of SARS-CoV-2-specific IgM and IgG by 29 PCR-confirmed COVID-19 cases and 124 negative controls. The results revealed a sensitivity of 69% and 93.1% for IgM and IgG, respectively, based solely on PCR-positivity due to the absence of a serological gold standard. The assay specificities were shown to be 100% for IgM and 99.2% for IgG. This indicates that the test is suitable for assessing previous virus exposure, although negative results may be unreliable during the first weeks after infection. More detailed studies on antibody responses during and post infection are urgently needed.
has issue date	2020-04-14(xsd:dateTime)
bibo:doi	10.1080/20008686.2020.1754538
bibo:pmid	32363011
has license	cc-by
sha1sum (hex)	a4660be6df902c34e11658e30722bff0b504429a
schema:url	https://doi.org/10.1080/20008686.2020.1754538
resource representing a document's title	Evaluation of a COVID-19 IgM and IgG rapid test; an efficient tool for assessment of past exposure to SARS-CoV-2
has PubMed Central identifier	PMC7178815
has PubMed identifier	32363011
schema:publication	Infect Ecol Epidemiol
resource representing a document's body	covid:a4660be6df902c34e11658e30722bff0b504429a#body_text
is schema:about of	named entity '15 minutes' named entity 'needed' named entity 'SARS-CoV-2' named entity 'serological' named entity 'potential' »more»

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