About: Epidemiology of respiratory viruses in bronchoalveolar lavage samples in a tertiary hospital

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Epidemiology of respiratory viruses in bronchoalveolar lavage samples in a tertiary hospital
Creator	Beuselinck, Kurt Lagrou, Katrien Padalko, Elizaveta Drieghe, Stefanie Ryckaert, Inge
source	Elsevier; Medline; PMC
abstract	BACKGROUND: The prevalence of respiratory viruses in adults is largely underexplored, as most studies focus on children. Additionally, in severely ill or immunocompromised adults, where respiratory infections are mostly attributed to bacteria and fungi; respiratory viruses can lead to severe complications. OBJECTIVES: To evaluate the epidemiology of respiratory viruses in bronchoalveolar lavage fluid (BAL) specimens from patients with lower respiratory tract disease. The study population consisted of different groups including immunocompetent patients (control patients), solid organ transplant recipients, patients with haematological malignancies and other immunocompromised adults. STUDY DESIGN: A total of 134 BAL fluid specimens collected during 2009–2011 were retrospectively assessed with the new commercial multiplex real-time PCR FTD Respiratory 21 Plus(®), targeting 18 different viruses and 2 atypical bacterial pathogens. RESULTS: Viral or atypical bacterial pathogens were detected in 29.1% of BAL fluid specimens. Coronaviruses were most prevalent (13.4%), followed by rhinoviruses (5.2%), RSV (4.5%) and bocaviruses (3.7%). Comparing the total number of viruses detected, a statistically significant difference was observed between the control group and patients with haematological malignancies (27.5% vs. 57.1%, p < 0.05). CONCLUSION: In conclusion, our study highlights the high prevalence of respiratory viruses in BAL fluid specimens from adult patients with lower respiratory tract disease. The methods to be used should be sensitive and cover a wide range of potential pathogens. The specific patient population can also influence the detection rates of respiratory viruses.
has issue date	2014-01-03(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2013.12.008
bibo:pmid	24447853
has license	no-cc
sha1sum (hex)	a2e53d0fa7f133152cb9a310420f68ccb1ed4483
schema:url	https://doi.org/10.1016/j.jcv.2013.12.008
resource representing a document's title	Epidemiology of respiratory viruses in bronchoalveolar lavage samples in a tertiary hospital
has PubMed Central identifier	PMC7172540
has PubMed identifier	24447853
schema:publication	J Clin Virol
resource representing a document's body	covid:a2e53d0fa7f133152cb9a310420f68ccb1ed4483#body_text
is schema:about of	named entity 'statistically' named entity 'observed' named entity 'prevalent' named entity 'viruses' named entity 'fungi' »more»

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