About: Optimizing treatment of respiratory tract infections in nursing homes: Nurse-initiated polymerase chain reaction testing

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Optimizing treatment of respiratory tract infections in nursing homes: Nurse-initiated polymerase chain reaction testing
Creator	Epi, Clin Stuart, Rhonda Deborah, N Dip, Grad Dowson Mbioethics, Leslie »more»
source	Elsevier; Medline; PMC
abstract	Background Diagnostic testing using polymerase chain reaction (PCR) is infrequently initiated for diagnosis of respiratory tract infections (RTIs) in nursing homes. The objectives of this study were to determine the feasibility of implementing nurse-initiated PCR testing of respiratory specimens in nursing home settings and to compare antibiotic prescribing prior to and during the implementation. Methods This was a pragmatic, historically controlled study in 3 nursing homes (181 total beds) in Melbourne, Australia. Results The number of PCR tests of respiratory specimens (over 12 months) increased from 5 to 67 when nurses could initiate the tests. Residents with RTI symptoms had a virus identified by PCR in 50.7% of tests, including 14 positive for influenza. Six outbreaks were identified. When clustering was taken into consideration, incidence rates of antibiotic days of therapy did not change (incidence rate ratio = 0.94, 95% confidence interval, 0.25-3.35, P = .92) despite identification of more viral pathogens. Conclusions In nursing homes, nurse-initiated PCR testing of respiratory specimens is feasible and useful in terms of identifying the cause of many RTIs and outbreaks, and viruses are common in this context. However, the current study suggests the availability of these test results alone does not impact antibiotic prescribing.
has issue date	2019-08-31(xsd:dateTime)
bibo:doi	10.1016/j.ajic.2019.02.001
bibo:pmid	30851997
has license	els-covid
sha1sum (hex)	a2d496bdd1d11f1a6859d923670235b38a848ea3
schema:url	https://doi.org/10.1016/j.ajic.2019.02.001
resource representing a document's title	Optimizing treatment of respiratory tract infections in nursing homes: Nurse-initiated polymerase chain reaction testing
has PubMed Central identifier	PMC7172091
has PubMed identifier	30851997
schema:publication	American Journal of Infection Control
resource representing a document's body	covid:a2d496bdd1d11f1a6859d923670235b38a848ea3#body_text
is schema:about of	named entity 'test' named entity 'settings' named entity 'confidence interval' named entity 'viral pathogens' named entity 'PCR' »more»

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