About: Acute exacerbation of COPD

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Acute exacerbation of COPD Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Acute exacerbation of COPD
Creator	Hui, David Shaw, Janet Ko, Fanny Chan, Ka Reid, David »more»
source	Medline; PMC
abstract	The literature of acute exacerbation of chronic obstructive pulmonary disease (COPD) is fast expanding. This review focuses on several aspects of acute exacerbation of COPD (AECOPD) including epidemiology, diagnosis and management. COPD poses a major health and economic burden in the Asia‐Pacific region, as it does worldwide. Triggering factors of AECOPD include infectious (bacteria and viruses) and environmental (air pollution and meteorological effect) factors. Disruption in the dynamic balance between the ‘pathogens’ (viral and bacterial) and the normal bacterial communities that constitute the lung microbiome likely contributes to the risk of exacerbations. The diagnostic approach to AECOPD varies based on the clinical setting and severity of the exacerbation. After history and examination, a number of investigations may be useful, including oximetry, sputum culture, chest X‐ray and blood tests for inflammatory markers. Arterial blood gases should be considered in severe exacerbations, to characterize respiratory failure. Depending on the severity, the acute management of AECOPD involves use of bronchodilators, steroids, antibiotics, oxygen and noninvasive ventilation. Hospitalization may be required, for severe exacerbations. Nonpharmacological interventions including disease‐specific self‐management, pulmonary rehabilitation, early medical follow‐up, home visits by respiratory health workers, integrated programmes and telehealth‐assisted hospital at home have been studied during hospitalization and shortly after discharge in patients who have had a recent AECOPD. Pharmacological approaches to reducing risk of future exacerbations include long‐acting bronchodilators, inhaled steroids, mucolytics, vaccinations and long‐term macrolides. Further studies are needed to assess the cost‐effectiveness of these interventions in preventing COPD exacerbations.
has issue date	2016-03-30(xsd:dateTime)
bibo:doi	10.1111/resp.12780
bibo:pmid	27028990
has license	no-cc
sha1sum (hex)	a14f032727ab00fbeb4f957f7e88e02b9979f49c
schema:url	https://doi.org/10.1111/resp.12780
resource representing a document's title	Acute exacerbation of COPD
has PubMed Central identifier	PMC7169165
has PubMed identifier	27028990
schema:publication	Respirology
resource representing a document's body	covid:a14f032727ab00fbeb4f957f7e88e02b9979f49c#body_text
is schema:about of	named entity 'varies' named entity 'patients' named entity 'factors' named entity 'WORKERS' named entity 'INTEGRATED' »more»

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software