About: Statistical methods for detecting molecular adaptation

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Statistical methods for detecting molecular adaptation Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Statistical methods for detecting molecular adaptation
source	Elsevier; Medline; PMC
abstract	Abstract The past few years have seen the development of powerful statistical methods for detecting adaptive molecular evolution. These methods compare synonymous and nonsynonymous substitution rates in protein-coding genes, and regard a nonsynonymous rate elevated above the synonymous rate as evidence for darwinian selection. Numerous cases of molecular adaptation are being identified in various systems from viruses to humans. Although previous analyses averaging rates over sites and time have little power, recent methods designed to detect positive selection at individual sites and lineages have been successful. Here, we summarize recent statistical methods for detecting molecular adaptation, and discuss their limitations and possible improvements.
has issue date	2000-12-01(xsd:dateTime)
bibo:doi	10.1016/s0169-5347(00)01994-7
bibo:pmid	11114436
has license	els-covid
sha1sum (hex)	8c27963589a2e59be28d0f9a789a773cc2868895
schema:url	https://doi.org/10.1016/s0169-5347%2800%2901994-7
resource representing a document's title	Statistical methods for detecting molecular adaptation
has PubMed Central identifier	PMC7134603
has PubMed identifier	11114436
schema:publication	Trends in Ecology & Evolution
resource representing a document's body	covid:8c27963589a2e59be28d0f9a789a773cc2868895#body_text
is schema:about of	named entity 'monophyletic' named entity 'codon' named entity 'probability' named entity 'likelihood-ratio test' named entity 'codon composition' »more»

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software