About: Multiple Thrombotic Events in a 67-Year-Old Man 2 Weeks After Testing Positive for SARS-CoV-2: A Case Report

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Multiple Thrombotic Events in a 67-Year-Old Man 2 Weeks After Testing Positive for SARS-CoV-2: A Case Report Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Multiple Thrombotic Events in a 67-Year-Old Man 2 Weeks After Testing Positive for SARS-CoV-2: A Case Report
Creator	Aiash, Hani Abde, Ade, Hanan De, Amish De, Eric »more»
source	Medline; PMC
abstract	Patient: Male, 67-year-old Final Diagnosis: Acute cardiac injury • COVID-19 • pulmonary embolism • stroke Symptoms: Confusion • diarrhea • dysarthria • fever • myalgia • sore throat Medication: — Clinical Procedure: Mechanical ventilation Specialty: Critical Care Medicine OBJECTIVE: Unusual clinical course BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for coronavirus disease 2019 (COVID-19), a pandemic respiratory illness. While many patients experience mild to moderate symptoms, severely affected patients often progress to acute respiratory distress syndrome (ARDS). Specific to COVID-19, abnormal coagulability appears to be a principal instigator in the progression of disease severity and mortality. In this report we summarize a case of COVID-19 in which extreme thrombophilia led to patient demise. CASE REPORT: A 67-year-old man in New York presented to the hospital 14 days after testing positive for SARS-CoV-2 at an outpatient site. His initial presenting symptoms included sore throat, headache, fever, and diarrhea. He was brought in by his wife after developing sudden onset confusion and dysarthria. The patient’s clinical picture, which was unstable on presentation, further deteriorated to involve significant desaturations, generalized seizure activity, and cardiac arrest requiring resuscitation. Upon return to spontaneous circulation, the patient required intensive care unit admission, mechanical ventilation, and vasopressor increases. Comprehensive workup uncovered coagulopathy with multiple thrombotic events involving the brain and lungs as well as radiographic evidence of severe lung disease. In the face of an unfavorable clinical picture, the family opted for comfort care measures. CONCLUSIONS: In this case report on a 67-year-old-man with COVID-19, we present an account of extreme hypercoagulability that led to multiple thrombotic events eventually resulting in the man’s demise. Abnormal coagulation 14 days from positive testing raises the question of whether outpatients with COVID-19 should be screened for hypercoagulability and treated with prophylactic anticoagulation/antiplatelet agents.
has issue date	2020-07-22(xsd:dateTime)
bibo:doi	10.12659/ajcr.925786
bibo:pmid	32694498
has license	cc-by-nc-nd
sha1sum (hex)	84778cd1bdf01ff9f5a4156debacdfb7bceb1e9b
schema:url	https://doi.org/10.12659/ajcr.925786
resource representing a document's title	Multiple Thrombotic Events in a 67-Year-Old Man 2 Weeks After Testing Positive for SARS-CoV-2: A Case Report
has PubMed Central identifier	PMC7394557
has PubMed identifier	32694498
schema:publication	Am J Case Rep
resource representing a document's body	covid:84778cd1bdf01ff9f5a4156debacdfb7bceb1e9b#body_text
is schema:about of	named entity 'Weeks' named entity 'SARS-CoV-2' named entity 'Report' named entity 'Case' named entity 'prophylactic' »more»

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software