About: Dynamics of neutralizing antibody titers in the months after SARS-CoV-2 infection

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About: Dynamics of neutralizing antibody titers in the months after SARS-CoV-2 infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Dynamics of neutralizing antibody titers in the months after SARS-CoV-2 infection
Creator	Bloom, Jesse Chu, Helen Logue, Jennifer Wolf, Caitlin King, Neil »more»
source	MedRxiv
abstract	Most individuals infected with SARS-CoV-2 develop neutralizing antibodies that target the viral spike protein. Here we quantify how levels of these antibodies change in the months following SARS-CoV-2 infection by examining longitudinal samples collected between {approx}30 and 152 days post-symptom onset from a prospective cohort of 34 recovered individuals with asymptomatic, mild, or moderate-severe disease. Neutralizing antibody titers declined an average of about four-fold from one to four months post-symptom onset. Importantly, our data are consistent with the expected early immune response to viral infection, where an initial peak in antibody levels is followed by a decline to a lower plateau. Additional studies of long-lived B-cells and antibody titers over longer time frames are necessary to determine the durability of immunity to SARS-CoV-2.
has issue date	2020-08-07(xsd:dateTime)
bibo:doi	10.1101/2020.08.06.20169367
has license	medrxiv
sha1sum (hex)	80bad96abf3f205197f81de11b27050a829918d3
schema:url	https://doi.org/10.1101/2020.08.06.20169367
resource representing a document's title	Dynamics of neutralizing antibody titers in the months after SARS-CoV-2 infection
resource representing a document's body	covid:80bad96abf3f205197f81de11b27050a829918d3#body_text
is schema:about of	named entity 'decline' named entity 'accompanied' named entity 'studies' named entity 'infection' named entity 'SARS-CoV-2' »more»

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