About: Efficacy of moist heat decontamination against various pathogens for the reuse of N95 respirators in the COVID-19 emergency

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About: Efficacy of moist heat decontamination against various pathogens for the reuse of N95 respirators in the COVID-19 emergency Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Efficacy of moist heat decontamination against various pathogens for the reuse of N95 respirators in the COVID-19 emergency
Creator	Collins, Cassidy Connolly, Rachel Gardecki, Joseph Gjore, Julian Jaber, Tareq »more»
topic	covid:711b7b0b662bd3fa5a8b58530753f3b162682f4a#this
source	MedRxiv
abstract	Decontamination of N95 respirators has become critical to alleviate PPE shortages for healthcare workers in the current COVID-19 emergency. The factors that are considered for the effective reuse of these masks are the fit, filter efficiency and decontamination/disinfection level both for SARS-CoV2, which is the causative virus for COVID-19, and for other organisms of concern in the hospital environment such as Staphylococcus aureus or Clostridium difficile. The efficacy of inactivation or eradication against various pathogens should be evaluated thoroughly to understand the level of afforded disinfection. Methods commonly used in the sterilization of medical devices such as ionizing radiation, vaporized hydrogen peroxide, and ethylene oxide can provide a high level of disinfection, defined as a 6 log10 reduction, against bacterial spores, considered the most resistant microorganisms. CDC guidance on the decontamination and reuse of N95s also includes the use of moist heat (60{degrees}C, 80% relative humidity, 15-30 min) as a possible recommendation based on literature showing preservation of fit efficiency and inactivation of H1N1 on spiked masks. Here, we explored the efficacy of using moist heat under these conditions as a decontamination method for an N95 respirator (3M 1860S, St. Paul, MN) against various pathogens with different resistance; enveloped RNA viruses, Gram (+/-) bacteria, and non-enveloped viruses.
has issue date	2020-05-19(xsd:dateTime)
bibo:doi	10.1101/2020.05.13.20100651
has license	medrxiv
sha1sum (hex)	711b7b0b662bd3fa5a8b58530753f3b162682f4a
schema:url	https://doi.org/10.1101/2020.05.13.20100651
resource representing a document's title	Efficacy of moist heat decontamination against various pathogens for the reuse of N95 respirators in the COVID-19 emergency
resource representing a document's body	covid:711b7b0b662bd3fa5a8b58530753f3b162682f4a#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/711b7b0b662bd3fa5a8b58530753f3b162682f4a
is schema:about of	named entity 'respirators' named entity 'critical' named entity 'organisms' named entity 'Clostridium' named entity 'pathogens' »more»

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