About: Pneumocystis jirovecii pneumonia as an initial manifestation of hyper-IgM syndrome in an infant: A case report

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About: Pneumocystis jirovecii pneumonia as an initial manifestation of hyper-IgM syndrome in an infant: A case report Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Pneumocystis jirovecii pneumonia as an initial manifestation of hyper-IgM syndrome in an infant: A case report
Creator	Chung, Nack-Gyun Kim, Danbi Jeong, Chul Shin, Ju Han, Beom
source	Medline; PMC
abstract	RATIONALE: Pneumocystis jirovecii causes severe pneumonia in immunocompromised hosts. Human immunodeficiency virus infection, malignancy, solid organ or hematopoietic cell transplantation, and primary immune deficiency compose the risk factors for Pneumocystis pneumonia (PCP) in children, and PCP can be an initial clinical manifestation of primary immune deficiency. PATIENT CONCERNS: A 5-month-old infant presented with cyanosis and tachypnea. He had no previous medical or birth history suggesting primary immune deficiency. He was diagnosed with interstitial pneumonia on admission. DIAGNOSES: He was diagnosed with PCP, and further evaluations revealed underlying X-linked hyper-IgM syndrome. INTERVENTIONS: He was treated with trimethoprim/sulfamethoxazole for PCP, and eventually received allogeneic hematopoietic cell transplantation for hyper-IgM syndrome. OUTCOMES: Twenty months have passed after transplantation without severe complications. LESSONS: PCP should be considered in infants presenting with severe interstitial pneumonia even in the absence of evidence of immune deficiency. Primary immune deficiency should also be suspected in infants diagnosed with PCP.
has issue date	2019-02-15(xsd:dateTime)
bibo:doi	10.1097/md.0000000000014559
bibo:pmid	30762803
has license	cc-by-nc-nd
sha1sum (hex)	709c30173f5cfdd55b8636f71cf76d3788a0553d
schema:url	https://doi.org/10.1097/md.0000000000014559
resource representing a document's title	Pneumocystis jirovecii pneumonia as an initial manifestation of hyper-IgM syndrome in an infant: A case report
has PubMed Central identifier	PMC6408131
has PubMed identifier	30762803
schema:publication	Medicine (Baltimore)
resource representing a document's body	covid:709c30173f5cfdd55b8636f71cf76d3788a0553d#body_text
is schema:about of	named entity 'CLINICAL MANIFESTATION' named entity 'PNEUMOCYSTIS PNEUMONIA' named entity 'PNEUMOCYSTIS JIROVECII' named entity 'HEMATOPOIETIC CELL TRANSPLANTATION' named entity 'HUMAN IMMUNODEFICIENCY VIRUS INFECTION' »more»

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