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Functional and cognitive outcomes after COVID-19 delirium
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covidontheweb.inria.fr
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Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Functional and cognitive outcomes after COVID-19 delirium
Creator
Affiliations,
Davis, Daniel
Eyres, Clodagh
Fabbri, Ambra
Humphries, Fiona
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source
MedRxiv
abstract
Purpose To ascertain delirium prevalence and outcomes in COVID-19. Methods We conducted a point-prevalence study in a cohort of COVID-19 inpatients at University College Hospital. Delirium was defined by DSM-IV criteria. The primary outcome was all-cause mortality at 4 weeks; secondary outcomes were physical and cognitive function. Results In 71 patients, 31 (42%) had delirium, of which only 19 had been recognised by the clinical team. At 4 weeks, 20 (28%) had died, 26 (36%) were interviewed by telephone and 21 (30%) remained as inpatients. Physical function was substantially worse in people after delirium (-39 points on functional scale/166, 95% CI -92 to -21, p=0.01) (Table 2). Mean cognitive scores at follow-up were similar and delirium was not associated with mortality in this sample. Conclusions Our findings indicate that delirium is common, yet under-recognised. Delirium is associated with functional impairments in the medium-term.
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2020-06-09
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bibo:doi
10.1101/2020.06.07.20115188
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medrxiv
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690b4c55373d5fe2fc6af6f19f75b378780cba66
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https://doi.org/10.1101/2020.06.07.20115188
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Functional and cognitive outcomes after COVID-19 delirium
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covid:690b4c55373d5fe2fc6af6f19f75b378780cba66#body_text
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named entity 'cognitive'
named entity 'excess mortality'
named entity 'older patients'
named entity 'critical care'
named entity 'DSM-IV'
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