About: Application of montmorillonite in bentonite as a pharmaceutical excipient in drug delivery systems

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About: Application of montmorillonite in bentonite as a pharmaceutical excipient in drug delivery systems Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Application of montmorillonite in bentonite as a pharmaceutical excipient in drug delivery systems
Creator	Kang, Naewon Kim, Dae-Duk Kim, Ji-Su Kim, Ki-Taek Lee, Jae-Young »more»
source	Medline; PMC
abstract	Montmorillonite is a multifunctional clay mineral and a major component of bentonite. Montmorillonite has been used in various industrial and pharmaceutical fields due to its unique characteristics, which include swelling and adsorption. The high adsorption capacity of montmorillonite contributes to increase drug entrapment and sustained-release of drugs. Montmorillonite generally sustains drug release in many formulations by strongly adsorbing to the drug. In addition, montmorillonite enhances the dissolution rate and bioavailability of hydrophobic drugs. Moreover, montmorillonite was applied to form composites with other polymer-based delivery systems. Thus, montmorillonite could be applied to formulate diverse drug delivery systems to control and/or improve the pharmaceutical properties of drugs, including solubility, dissolution rate, and absorption. In this review, perspectives of applying montmorillonite as a pharmaceutical excipient in drug delivery systems are discussed.
has issue date	2016-05-21(xsd:dateTime)
bibo:doi	10.1007/s40005-016-0258-8
bibo:pmid	32226640
has license	no-cc
sha1sum (hex)	612f17cded1defc86125c686b933fde361879480
schema:url	https://doi.org/10.1007/s40005-016-0258-8
resource representing a document's title	Application of montmorillonite in bentonite as a pharmaceutical excipient in drug delivery systems
has PubMed Central identifier	PMC7100357
has PubMed identifier	32226640
schema:publication	J Pharm Investig
resource representing a document's body	covid:612f17cded1defc86125c686b933fde361879480#body_text
is schema:about of	named entity 'PHARMACEUTICAL EXCIPIENT' named entity 'SOLUBILITY' named entity 'SWELLING' named entity 'IS A' named entity 'DELIVERY SYSTEMS' »more»

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