About: Characterization and mutational analysis of haemagglutinin and neuraminidase of H3N2 and H1N1pdm09 human influenza A viruses in Egypt

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About: Characterization and mutational analysis of haemagglutinin and neuraminidase of H3N2 and H1N1pdm09 human influenza A viruses in Egypt Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Characterization and mutational analysis of haemagglutinin and neuraminidase of H3N2 and H1N1pdm09 human influenza A viruses in Egypt
Creator	Mohamed, M Soliman, May Kamel, Mahmoud Abdel-Moneim, S Ahmed, • »more»
source	Medline; PMC
abstract	Seasonal influenza viruses constitute a major global concern. Currently, H3N2 and H1N1pdm09 are the commonly circulating influenza A viruses. The haemagglutin and neuraminidase genes of influenza A(H3N2) and A(H1N1)pdm09 viruses from Egyptian paediatric patients with respiratory distress were sequenced. Mutational analysis of all published sequences from Egypt was evolutionary tracked for both HA and NA genes. Phylogenetic analysis of H3N2 HA showed that the Egyptian strains belong to 3C2 subclade while Egyptian A(H1N1)pdm09 strains belong to 6B1 subclade. Some Egyptian A(H1N1)pdm09, 2013–2014, strains form a new subclade; 6B3. High score of mutations were recorded in HA of H1N1pdm09 but higher was recorded in H3N2 strains. These findings confirmed a high mutation rate of influenza A subtypes specially H3N2 strains.
has issue date	2020-06-03(xsd:dateTime)
bibo:doi	10.1007/s13337-020-00609-8
bibo:pmid	32837970
has license	no-cc
sha1sum (hex)	527a91cf60ecf55f76b2c4c25c94da1df9ec8cb5
schema:url	https://doi.org/10.1007/s13337-020-00609-8
resource representing a document's title	Characterization and mutational analysis of haemagglutinin and neuraminidase of H3N2 and H1N1pdm09 human influenza A viruses in Egypt
has PubMed Central identifier	PMC7268970
has PubMed identifier	32837970
schema:publication	Virusdisease
resource representing a document's body	covid:527a91cf60ecf55f76b2c4c25c94da1df9ec8cb5#body_text
is schema:about of	named entity 'high' named entity 'Seasonal influenza' named entity 'mutational' named entity 'SEQUENCES' named entity 'PUBLISHED' »more»

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