About: Nano-clays as Potential Pseudo-antibodies for COVID-19

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Nano-clays as Potential Pseudo-antibodies for COVID-19
Creator	Abduljauwad, Sahel Ahmed, Habib-Ur-Rehman Habib, Taimur
source	Medline; PMC
abstract	Despite several efforts, the development of an effective vaccine for COVID-19 may take a much longer time. Traditional/natural medicine, already experienced by humans, could be an earlier solution. Considering the research team’s experience in using nano-clays as high-affinity material for cancer metastasis, melanoma treatment, and bone regeneration, we propose to use these nano-clays for the prevention/treatment of COVID-19. Owing to high affinity, nano-clays would capture the viruses before the latter get engaged with human hACE2. In this study, molecular-level simulations and modeling of the interaction of coronavirus spike and hACE2 proteins were performed with and without nano-clays. The results showed a very high level of affinity/cohesiveness among SARS-CoV-2 spike and nano-clays as compared to the one between the former and hACE2. We premise that these nano-clays since already being used as drug carriers could also be injected as “clays-alone” medicine. Recommendations have also been provided for future in vitro and in vivo studies.
has issue date	2020-08-28(xsd:dateTime)
bibo:doi	10.1186/s11671-020-03403-z
bibo:pmid	32857226
has license	cc-by
sha1sum (hex)	4ebff9cd9717094d240efde829da9e465d20e63b
schema:url	https://doi.org/10.1186/s11671-020-03403-z
resource representing a document's title	Nano-clays as Potential Pseudo-antibodies for COVID-19
has PubMed Central identifier	PMC7453700
has PubMed identifier	32857226
schema:publication	Nanoscale Res Lett
resource representing a document's body	covid:4ebff9cd9717094d240efde829da9e465d20e63b#body_text
is schema:about of	named entity 'affinity' named entity 'injected' named entity 'engaged' named entity 'experienced' named entity 'viruses' »more»

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