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About:
Feasibility of non-invasive nitric oxide inhalation in acute hypoxic respiratory failure: potential role during the COVID-19 pandemic
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covidontheweb.inria.fr
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Feasibility of non-invasive nitric oxide inhalation in acute hypoxic respiratory failure: potential role during the COVID-19 pandemic
Creator
Prof, A
Shekar, Kiran
Ramanan, Mahesh
Siuba, Matthew
Cornmell, George
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source
MedRxiv
abstract
Acute hypoxemic respiratory failure (ARF) is characterized by both lower arterial oxygen and carbon dioxide tensions in the blood. First line treatment for ARF includes oxygen therapy,intially admininstered non invasively using nasal prongs, high flow nasal cannulae or masks. Invasive mechancial ventilation (IMV) is usually reserved for patients who are unable to maintain their airway, those with worsening hypoxemia, or those who develop respiratory muscle fatigue and consequent hypercapnia. Inhaled nitric oxide (iNO) gas is known to improve oxygenation in patients with ARF by manipulating ventilation-perfusion matching. Addition of iNO may potentially alleviate the need for IMV in selected patients. This article demonstrates the feasibility of this technique based on our experience of patients with hypoxemic ARF. This technique may also be considered for patients with hypoxic ARF in setting of COVID-19.
has issue date
2020-05-20
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bibo:doi
10.1101/2020.05.17.20082123
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medrxiv
sha1sum (hex)
4d5f8d200cf53d7b26d01ee3b8cbb991e6985f93
schema:url
https://doi.org/10.1101/2020.05.17.20082123
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Feasibility of non-invasive nitric oxide inhalation in acute hypoxic respiratory failure: potential role during the COVID-19 pandemic
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covid:4d5f8d200cf53d7b26d01ee3b8cbb991e6985f93#body_text
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schema:about
of
named entity 'hypoxemic'
named entity 'hypercapnia'
named entity 'USUALLY'
named entity 'IMV'
named entity 'Acute'
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