About: Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study
Creator	Wang, Xi Jin, Yang Chang, Christopher Cao, Feng Wang, Runsheng »more»
source	Medline; PMC
abstract	Rationale: The global death toll from coronavirus disease (COVID-19) virus as of May 12, 2020, exceeds 286,000. The risk factors for death were attributed to advanced age and comorbidities but have not been accurately defined. Objectives: To report the clinical features of 85 fatal cases of COVID-19 in two hospitals in Wuhan. Methods: Medical records were collected of 85 fatal cases of COVID-19 between January 9, 2020, and February 15, 2020. Information recorded included medical history, exposure history, comorbidities, symptoms, signs, laboratory findings, computed tomographic scans, and clinical management. Measurements and Main Results: The median age of the patients was 65.8 years, and 72.9% were male. Common symptoms were fever (78 [91.8%]), shortness of breath (50 [58.8%]), fatigue (50 [58.8%]), and dyspnea (60 [70.6%]). Hypertension, diabetes, and coronary heart disease were the most common comorbidities. Notably, 81.2% of patients had very low eosinophil counts on admission. Complications included respiratory failure (80 [94.1%]), shock (69 [81.2%]), acute respiratory distress syndrome (63 [74.1%]), and arrhythmia (51 [60%]), among others. Most patients received antibiotic (77 [90.6%]), antiviral (78 [91.8%]), and glucocorticoid (65 [76.5%]) treatments. A total of 38 (44.7%) and 33 (38.8%) patients received intravenous immunoglobulin and IFN-α2b, respectively. Conclusions: In this depictive study of 85 fatal cases of COVID-19, most cases were males aged over 50 years with noncommunicable chronic diseases. The majority of the patients died of multiple organ failure. Early onset of shortness of breath may be used as an observational symptom for COVID-19 exacerbations. Eosinophilopenia may indicate a poor prognosis. A combination of antimicrobial drugs did not offer considerable benefit to the outcome of this group of patients.
has issue date	2020-06-01(xsd:dateTime)
bibo:doi	10.1164/rccm.202003-0543oc
bibo:pmid	32242738
has license	cc-by-nc-nd
sha1sum (hex)	478e1dcb3d627508145a55c901f234f8ea536e6a
schema:url	https://doi.org/10.1164/rccm.202003-0543oc
resource representing a document's title	Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study
has PubMed Central identifier	PMC7258652
has PubMed identifier	32242738
schema:publication	Am J Respir Crit Care Med
resource representing a document's body	covid:478e1dcb3d627508145a55c901f234f8ea536e6a#body_text
is schema:about of	named entity 'COVID-19' named entity 'coronavirus' named entity 'COVID-19' named entity 'antibiotics' named entity 'bacterial cultures' »more»

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software