About: Clinical meanings of rapid serological assay in patients tested for SARS-Co2 RT-PCR

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About: Clinical meanings of rapid serological assay in patients tested for SARS-Co2 RT-PCR Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Clinical meanings of rapid serological assay in patients tested for SARS-Co2 RT-PCR
Creator	Cafagna, Vito Centrone, Francesca Chironna, Maria De Palma, Giuseppe De Summa, Simona »more»
source	MedRxiv
abstract	Background RT-PCR test for identifiction of viral nucleic acid is the current standard diagnostic method for the diagnosis of COVID-19 disease but technical reasons limit the utilization of this assay on large scale screenings. Method We verified in a consecutive series of 191 symptomatic patients the clinical information that new rapid serological colorimetric test qualitatively analyzing IgM/IgG expression can provide with respect to standard assay and with respect to clinical outcome of patients. Results Rapid serological test showed a sensitivity of 30% and a specificity of 89% with respect to the standard assay but, interestingly, these performances improve after 8 days of symptoms appearance. After 10 days of symptoms the predictive value of rapid serological test is higher than that of standard assay. When the behaviour of the two immunoglobulins was evaluated with respect to time length of symptoms appearance, no significant difference in immunoglobulins behaviour was shown. Conclusions The rapid serological test analyzed in the present study is candidate to provide information on immunoreaction of the subject to COVID-19 exposure.
has issue date	2020-04-06(xsd:dateTime)
bibo:doi	10.1101/2020.04.03.20052183
has license	medrxiv
sha1sum (hex)	47236f3c7fe98fc3ab9a033df5d29ec778509a09
schema:url	https://doi.org/10.1101/2020.04.03.20052183
resource representing a document's title	Clinical meanings of rapid serological assay in patients tested for SARS-Co2 RT-PCR
resource representing a document's body	covid:47236f3c7fe98fc3ab9a033df5d29ec778509a09#body_text
is schema:about of	named entity 'PATIENTS' named entity 'STANDARD' named entity 'EVALUATED' named entity 'NEW' named entity 'CURRENT' »more»

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