About: Relationship between the treatment and the evolution of the clinical course in scouring Merino lambs from “La Serena” (Southwest Spain)

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About: Relationship between the treatment and the evolution of the clinical course in scouring Merino lambs from “La Serena” (Southwest Spain) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Relationship between the treatment and the evolution of the clinical course in scouring Merino lambs from “La Serena” (Southwest Spain)
Creator	Alonso, J Andrés, S Gómez, L Jiménez, A López, F »more»
source	Elsevier; Medline; PMC
abstract	Abstract This work investigated the link between the type of treatment and the clinical evolution of lambs suffering from diarrhoea attributed to non-enterotoxigenic Escherichia coli. Two hundred and forty scouring lambs, and 25 healthy lambs selected as control, were used in this trial. The faecal samples from the scouring lambs were positive to non-enterotoxigenic E. coli. All the scouring lambs received supportive care and they were randomly allotted to two groups of 120 animals (treated group and untreated group). The lambs in the treated group were given two daily doses of 20mg/kg live weight spectinomycin for 3 days, while the other group of lambs (untreated group) did not receive any antibiotic. Serum endotoxin was higher in the treated lambs. The combined infection of E. coli + Proteus mirabilis was the most frequent microbiological result in the deceased treated lambs, while the only enteric pathogen isolated in the untreated lambs submitted to necroscopy was E. coli. The pathological findings most commonly recorded in the untreated lambs were suggestive of a generalized inflammatory process attributed to colibacilosis, while the lesions in the treated lambs might correspond to an enterotoxoemic process. The overproduction of P. mirabilis might be consequence of the antibiotic treatment and it would be the most probable cause of the endotoxemia, the high mortality rate and the pathological findings in the treated lambs. Therefore, a supportive care without antibiotics does not lead to a poorer chance of survival in lambs with diarrhoea attributed to non-enterotoxigenic E. coli.
has issue date	2008-05-31(xsd:dateTime)
bibo:doi	10.1016/j.smallrumres.2008.01.005
bibo:pmid	32288216
has license	els-covid
sha1sum (hex)	46c70e3d26e13df6936db2fc7be4831726fa4668
schema:url	https://doi.org/10.1016/j.smallrumres.2008.01.005
resource representing a document's title	Relationship between the treatment and the evolution of the clinical course in scouring Merino lambs from “La Serena” (Southwest Spain)
has PubMed Central identifier	PMC7135016
has PubMed identifier	32288216
schema:publication	Small Ruminant Research
resource representing a document's body	covid:46c70e3d26e13df6936db2fc7be4831726fa4668#body_text
is schema:about of	named entity 'lesions' named entity 'overproduction' named entity 'daily' named entity 'pathological' named entity 'process' »more»

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