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About:
Simulation of COVID-19 Incubation Period and the Effect of Probability Distribution Functionon Model Training Using MIMANSA
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Academic Article
research paper
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Covid-on-the-Web dataset
title
Simulation of COVID-19 Incubation Period and the Effect of Probability Distribution Functionon Model Training Using MIMANSA
Creator
Kulkarni, Padmaj
Patel, Abhilasha
Vaidya, Vinay
Welling, Arpita
source
MedRxiv
abstract
Coronavirus disease 2019 (COVID-19) has infected people all over the world. While scientists are busy finding a vaccine and medicine, it becomes difficult to control the spread and manage patients. Mathematical models help one get a better feel for the challenges in patient management. With this in mind, our team developed a model called Multilevel Integrated Model with a Novel Systems Approach (MIMANSA). MIMANSA is a multi-parametric model. One of the challenges in the design of MIMANSA was to simulate the incubation period of coronavirus. The incubation period decides when virus-infected patients would show symptoms. The probability distribution function (PDF), when applied to the number of virus-infected cases, gives a good representation of the process of the incubation period. The probability distribution functions can take various forms. In this paper, we explore a variety of PDFs and their impact on parameter estimation in the MIMANSA model. For our experiments, we used Weibull, Gaussian, uniform, and Gamma distribution. To ensure a fair comparison of Weibull, Gaussian, and Gamma distribution, we matched the peak value of the distribution. Our results show that the Weibull distribution with shape 7.7 and scale 7 for 14 days gives a better training model and predictions.
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2020-06-20
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10.1101/2020.06.18.20134460
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medrxiv
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3bb89ce9a98827c1b381df956381bc1d2f02f6ca
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https://doi.org/10.1101/2020.06.18.20134460
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Simulation of COVID-19 Incubation Period and the Effect of Probability Distribution Functionon Model Training Using MIMANSA
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covid:3bb89ce9a98827c1b381df956381bc1d2f02f6ca#body_text
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named entity 'Coronavirus disease 2019'
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