About: Mixed Chinese herbs and Western medicine for novel coronavirus disease 2019 (COVID-19): a mixed method review

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Mixed Chinese herbs and Western medicine for novel coronavirus disease 2019 (COVID-19): a mixed method review
Creator	Zhang, Yong Goh, W Miguel, Robby Student, Tcm Tai, »more»
source	MedRxiv
abstract	Background: Coronavirus disease 2019 (COVID-19) is a pandemic affecting millions around the world. There is no existing pharmaceutical treatment that is known to be effective. Preliminary data shows that San Yao San Fang (SYSF) has clinical benefits in patients with COVID-19. The aim of this paper is to review existing data regarding the use of formulas within San Yao San Fang in the treatment of COVID-19 Search Strategy: We searched through 5 databases for studies on SYSF and patients with COVID-19 through April 2020. Eligibility Criteria: We included studies that included formulas within San Yao San Fang with or without Western interventions against Western interventions. Main results: We included 7 studies involving 532 patients. SYSF combined with Western interventions improved the recovery rate of symptoms such as fever (Risk Ratio (RR) 0.40 (95% CI 0.24 to 0.66, P < 0.01)), cough (RR 0.56 (95% CI 0.38 to 0.82, P < 0.01)) and fatigue (RR 0.61 (95% CI 0.47 to 0.78, P < 0.01)) and other symptoms such as headache, gastrointestinal symptoms, myalgia, dyspnoea and chest tightness (RR 0.63 (95% CI 0.47 to 0.83, P < 0.01)) as compared to the control group. SYSF combined with Western interventions reduced the duration of fever as compared to the control group. (Mean difference (MD) -1.18 (95% CI -1.45 to -0.91, P < 0.01)) In regards to adverse events, there is no statistical difference between the treatment group and the control group. (RR 1.62 (95% CI 0.83 to 3.17, P = 0.16)). SYSF combined with Western interventions did not show to significantly reduce duration of hospitalisation as compared to the control group. (MD -0.73 (95% CI -5.19 to 3.73, P = 0.75)) Conclusion: SYSF appears to be clinically effective and safe. Further research is required to ensure the efficacy of SYSF.
has issue date	2020-05-18(xsd:dateTime)
bibo:doi	10.1101/2020.05.11.20098111
has license	medrxiv
sha1sum (hex)	3a5060a65d60e1d373a6b78a4af7f40d97685a32
schema:url	https://doi.org/10.1101/2020.05.11.20098111
resource representing a document's title	Mixed Chinese herbs and Western medicine for novel coronavirus disease 2019 (COVID-19): a mixed method review
resource representing a document's body	covid:3a5060a65d60e1d373a6b78a4af7f40d97685a32#body_text
is schema:about of	named entity 'Western medicine' named entity 'COVID-19' named entity 'coronavirus disease 2019' named entity 'coronavirus disease 2019' named entity 'Chinese herbs' »more»

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