About: New EEG parameters correlated with sevoflurane concentration in dogs: tau and burst

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	New EEG parameters correlated with sevoflurane concentration in dogs: tau and burst
Creator	Hagihira, Satoshi Haruna, Taichi Koyama, Chika Yamashita, Kazuto
source	ArXiv
abstract	Background: Electroencephalographic (EEG) indicators for anaesthesia depth are being developed. Here, we propose novel EEG parameters created by using two kinds of waveforms discriminated by voltage thresholds from a new perspective. Methods: Six young-adult beagles and 6 senior beagles were anaesthetised with end-tidal sevoflurane (SEV) of 2.0%-4.0% in 0.5% intervals, and 2-channel EEG (256 Hz) was recorded. Two events were discriminated: a consecutive part ({/tau}) with a peak-to-peak potential difference (Vpp) within 1-6, 8, 12, or 20 mcrV, and another part (burst) with Vpp outside the threshold. Number of {/tau} (N{/tau}), mean {/tau} duration (M{/tau}), total percentage of {/tau} (SR{/tau}), mean burst duration (Mbst), and amplitude of burst (Abst) were evaluated as anaesthesia depth indicators using Pearsons correlation coefficients (r). Results: When Vpp was near the suppression wave threshold, N{/tau} had the highest correlation with SEV in both groups. As SEV was increased until onset of burst suppression, N{/tau} decreased, M{/tau} remained unchanged, and Mbst and Abst increased. In the young-adult group, mean \|r\| exceeded 0.95 for N{/tau} with Vpp of 4-6 mcrV, for Mbst with Vpp of 8-12 mcrV, and for Abst with Vpp of 4-12 mcrV. In the senior group, r exceeded 0.90 for N{/tau} with Vpp of 4 mcrV and for Abst with Vpp of 5-12 mcrV. Conclusion: We developed new EEG parameters that were almost perfectly correlated with volatile anaesthetic concentrations using traditional bipolar recording. This study suggests that the effect of anaesthetics on EEG can be investigated from two directions: pacemaker ({/tau}) and generator (burst).
has issue date	2019-10-07(xsd:dateTime)
has license	arxiv
sha1sum (hex)	386ce8d26602274f6cb3c7098e623f273556701a
resource representing a document's title	New EEG parameters correlated with sevoflurane concentration in dogs: tau and burst
resource representing a document's body	covid:386ce8d26602274f6cb3c7098e623f273556701a#body_text
is schema:about of	named entity 'senior' named entity 'young-adult' named entity 'events' named entity 'correlation coefficients' named entity 'generator' »more»

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