About: A community-deployable SARS-CoV-2 screening test using raw saliva with 45 minutes sample-to-results turnaround

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About: A community-deployable SARS-CoV-2 screening test using raw saliva with 45 minutes sample-to-results turnaround Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	A community-deployable SARS-CoV-2 screening test using raw saliva with 45 minutes sample-to-results turnaround
Creator	Barbachano-Guerrero, Arturo Yang, Qing Meyerson, Nicholas Sawyer, Sara Gilchrist, Alison »more»
source	MedRxiv
abstract	Up to 70% of SARS-CoV-2 infections in working- and school-age people are asymptomatic (Poletti et al., 2020), creating anxiety over reopening workplaces and schools around the world. In the absence of effective treatments or a vaccine, peace of mind will come only with community-based SARS-CoV-2 screening, where many people are tested on a regular basis. However, recent models show that short sample-to-answer turnaround time will be a critical property of effective screening strategies (Larremore et al., 2020). Here, we describe an RT-LAMP test for SARS-CoV-2 in raw saliva that takes about 45 minutes from sample to answer and requires only simple equipment (pipettes and a heating source). The assay has a limit of detection of 100 virions per microliter, and targets two separate regions of the SARS-CoV-2 genome. By combining rapid sample-to-answer turnaround time with the use of saliva, our RT-LAMP assay provides a low-complexity, portable, and robust system for real-time community screening.
has issue date	2020-07-17(xsd:dateTime)
bibo:doi	10.1101/2020.07.16.20150250
has license	medrxiv
sha1sum (hex)	2e6020ee37c82f42b9e3b5c8a0ce6bb4d6a5a208
schema:url	https://doi.org/10.1101/2020.07.16.20150250
resource representing a document's title	A community-deployable SARS-CoV-2 screening test using raw saliva with 45 minutes sample-to-results turnaround
resource representing a document's body	covid:2e6020ee37c82f42b9e3b5c8a0ce6bb4d6a5a208#body_text
is schema:about of	named entity 'saliva' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'chelating agent' named entity 'SARS-CoV-2' »more»

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