About: Distribution of infectious bronchitis virus strains in different organs and evidence of vertical transmission in natural infection

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Distribution of infectious bronchitis virus strains in different organs and evidence of vertical transmission in natural infection
Creator	Bressan, Gustavo Abelardo, • De Almeida, Rogéria Fietto, Rangel Lopes, Juliana »more»
source	Medline; PMC
abstract	On the basis of partial sequencing of the infectious bronchitis virus (IBV) S1 gene, this study investigated the molecular diversity of the virus in two life periods of a batch of breeding hens at the field level. The chicks were vaccinated against IBV on the second day of life with the vaccine Ma5, but at the age of 18 days, they exhibited clinical signs and macroscopic lesions compatible with avian infectious bronchitis (IB). In the clinical disease stage, the Ma5 vaccine strain was detected in the trachea, lungs, and small intestine of the chicks, while IBV variants were detected in the bursa of Fabricius and kidneys. Subsequently, new samples were collected from the same batch at the end of the production cycle. In this phase, the Ma5 vaccine strain was detected in the kidneys, small intestine, and oviduct of the hens. However, a previously unidentified IBV variant was found in the cecal tonsils. Additionally, a fragment of viral RNA with that was completely identical to the corresponding region of the Ma5 vaccine was detected in the allantoic fluid of viable embryos from the hens under study after 18 days of incubation. These findings suggest that, in addition to the Ma5 vaccine, other strains of IBV variants can coexist, seeming to establish a chronic infection in the chickens, and that they can potentially be transmitted vertically. These results may assist in immunoprophylaxis control programs against IBV. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-016-3030-5) contains supplementary material, which is available to authorized users.
has issue date	2016-09-01(xsd:dateTime)
bibo:doi	10.1007/s00705-016-3030-5
bibo:pmid	27586414
has license	no-cc
sha1sum (hex)	2b8ae6e6566252b0c6292ffa2c79c66fd924d346
schema:url	https://doi.org/10.1007/s00705-016-3030-5
resource representing a document's title	Distribution of infectious bronchitis virus strains in different organs and evidence of vertical transmission in natural infection
has PubMed Central identifier	PMC7087270
has PubMed identifier	27586414
schema:publication	Arch Virol
resource representing a document's body	covid:2b8ae6e6566252b0c6292ffa2c79c66fd924d346#body_text
is schema:about of	named entity 'identical' named entity 'evidence' covid:arg/2b8ae6e6566252b0c6292ffa2c79c66fd924d346 named entity 'viable' named entity 'IBV' »more»

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