About: The relationship between preoperative creatinine clearance and outcomes for patients undergoing liver transplantation: a retrospective observational study

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About: The relationship between preoperative creatinine clearance and outcomes for patients undergoing liver transplantation: a retrospective observational study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	The relationship between preoperative creatinine clearance and outcomes for patients undergoing liver transplantation: a retrospective observational study
Creator	Béchir, Markus Cottini, Silvia Oberkofler, Christian Schuepbach, Reto Scherrer, Marcel »more»
source	PMC
abstract	BACKGROUND: Renal failure with following continuous renal replacement therapy is a major clinical problem in liver transplant recipients, with reported incidences of 3% to 20%. Little is known about the significance of postoperative acute renal failure or acute-on-chronic renal failure to postoperative outcome in liver transplant recipients. METHODS: In this post hoc analysis we compared the mortality rates of 135 consecutive liver transplant recipients over 6 years in our center subject to their renal baseline conditions and postoperative RRT. We classified the patients into 4 groups, according to their preoperative calculated Cockcroft formula and the incidence of postoperative renal replacement therapy. Data then were analyzed in regard to mortality rates and in addition to pre- and peritransplant risk factors. RESULTS: There was a significant difference in ICU mortality (p=.008), hospital mortality (p=.002) and cumulative survival (p<.0001) between the groups. The highest mortality rate occurred in the group with RRT and normal baseline kidney function (20% ICU mortality, 26.6% hospital mortality and 50% cumulative 1-year mortality, respectively). The hazard ratio in this group was 9.6 (CI 3.2-28.6, p=.0001). CONCLUSION: This study shows that in liver transplant recipient’s acute renal failure with postoperative RRT is associated with mortality and the mortality rate is higher than in patients with acute-on-chronic renal failure and postoperative renal replacement therapy.
has issue date	2013-02-14(xsd:dateTime)
bibo:doi	10.1186/1471-2369-14-37
bibo:pmid	23409777
has license	cc-by
sha1sum (hex)	2b83892be9ff73eecd7ed333c57853db7a9fecc1
schema:url	https://doi.org/10.1186/1471-2369-14-37
resource representing a document's title	The relationship between preoperative creatinine clearance and outcomes for patients undergoing liver transplantation: a retrospective observational study
has PubMed Central identifier	PMC3582487
has PubMed identifier	23409777
schema:publication	BMC Nephrol
resource representing a document's body	covid:2b83892be9ff73eecd7ed333c57853db7a9fecc1#body_text
is schema:about of	named entity 'Renal failure' named entity 'observational study' named entity 'liver transplantation' named entity 'kidney' named entity 'renal impairment' »more»

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