About: Overview of lethal human coronaviruses

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Overview of lethal human coronaviruses Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Overview of lethal human coronaviruses
Creator	Zhang, Shu Cheng, Wei Chen, Bin Han, Ruiying Tian, Er-Kang »more»
source	Medline; PMC
abstract	Coronavirus infections of multiple origins have spread to date worldwide, causing severe respiratory diseases. Seven coronaviruses that infect humans have been identified: HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1, SARS-CoV, MERS-CoV, and SARS-CoV-2. Among them, SARS-CoV and MERS-CoV caused outbreaks in 2002 and 2012, respectively. SARS-CoV-2 (COVID-19) is the most recently discovered. It has created a severe worldwide outbreak beginning in late 2019, leading to date to over 4 million cases globally. Viruses are genetically simple, yet highly diverse. However, the recent outbreaks of SARS-CoV and MERS-CoV, and the ongoing outbreak of SARS-CoV-2, indicate that there remains a long way to go to identify and develop specific therapeutic treatments. Only after gaining a better understanding of their pathogenic mechanisms can we minimize viral pandemics. This paper mainly focuses on SARS-CoV, MERS-CoV, and SARS-CoV-2. Here, recent studies are summarized and reviewed, with a focus on virus–host interactions, vaccine-based and drug-targeted therapies, and the development of new approaches for clinical diagnosis and treatment.
has issue date	2020-06-10(xsd:dateTime)
bibo:doi	10.1038/s41392-020-0190-2
bibo:pmid	32533062
has license	cc-by
sha1sum (hex)	23668e27213097e9df6f1138db6d24a39c7d3aa9
schema:url	https://doi.org/10.1038/s41392-020-0190-2
resource representing a document's title	Overview of lethal human coronaviruses
has PubMed Central identifier	PMC7289715
has PubMed identifier	32533062
schema:publication	Signal Transduct Target Ther
resource representing a document's body	covid:23668e27213097e9df6f1138db6d24a39c7d3aa9#body_text
is schema:about of	named entity 'discovered' named entity 'SARS-CoV' named entity 'SARS-CoV' named entity 'develop' named entity 'MERS-CoV' »more»

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software