About: Factors associated with development of early and late pulmonary hypertension in preterm infants with bronchopulmonary dysplasia

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About: Factors associated with development of early and late pulmonary hypertension in preterm infants with bronchopulmonary dysplasia Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Factors associated with development of early and late pulmonary hypertension in preterm infants with bronchopulmonary dysplasia
Creator	Abraham, Boban Goto, Lisa Mowes, Anja Sheth, Sudip Bhandari, •
source	PMC
abstract	OBJECTIVE: To investigate factors associated with development of early and late pulmonary hypertension (E/LPH) in preterm infants with bronchopulmonary dysplasia (BPD). STUDY DESIGN: A retrospective case-control observational study of preterm infants with BPD admitted to a level IV referral neonatal intensive care unit over 5 years. We compared pre- and postnatal characteristics between infants with or without BPD-associated EPH and LPH. RESULTS: Fifty-nine out of 220 infants (26.8%) had LPH, while 85 out of 193 neonates (44%) had EPH. On multiple logistic regression, novel factors associated with development of BPD–LPH included presence of maternal diabetes, EPH, tracheostomy, tracheitis, intraventricular hemorrhage (IVH, grade ≥3) and systemic steroid use. For EPH, these were maternal diabetes, IVH grade ≥3, high frequency ventilator use, and absence of maternal antibiotics use. CONCLUSION: We identified novel factors and confirmed previously established factors with development of LPH and EPH, which can help develop a screening strategy in BPD patients.
has issue date	2019-11-13(xsd:dateTime)
bibo:doi	10.1038/s41372-019-0549-9
bibo:pmid	31723236
has license	no-cc
sha1sum (hex)	16ab6428a3b11e3af585a22d060ac438e3b310df
schema:url	https://doi.org/10.1038/s41372-019-0549-9
resource representing a document's title	Factors associated with development of early and late pulmonary hypertension in preterm infants with bronchopulmonary dysplasia
has PubMed Central identifier	PMC7223406
has PubMed identifier	31723236
schema:publication	J Perinatol
resource representing a document's body	covid:16ab6428a3b11e3af585a22d060ac438e3b310df#body_text
is schema:about of	named entity 'dysplasia' named entity 'late' named entity 'referral' named entity 'EPH' named entity 'LPH' »more»

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