About: An ORF-2a protein is not present at a significant level in virions of the arterivirus lactate dehydrogenase-elevating virus

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About: An ORF-2a protein is not present at a significant level in virions of the arterivirus lactate dehydrogenase-elevating virus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	An ORF-2a protein is not present at a significant level in virions of the arterivirus lactate dehydrogenase-elevating virus
Creator	Plagemann, Peter
source	Elsevier; Medline; PMC
abstract	Abstract MRNA2 of the arteriviruses lactate dehydrogenase-elevating virus (LDV) and equine arteritis virus (EAV) encodes two proteins that are read in different frames, an about 26 kDa minor envelope glycoprotein and an about 8 kDa protein that lacks N-glycosylation sites and a signal peptide, but possesses a central hydrophobic segment. Recent studies have shown that both proteins of EAV are translated from mRNA 2 in EAV infected BHK cells, that the 8 kDa protein is membrane associated and that small amounts of it are recovered in purified virions (Snijder, E.J., van Tol, H., Pederson, K.W., Raamsman, M.J.B., de Vries, A.A.F., 1999. Identification of a novel structural protein of arteriviruses. J. Virol. 73, 6335–6345). The authors concluded that the 8 kDa protein is another arterivirus envelope protein and designated it E protein. However, we have not detected a significant level of an 8 kDa protein in LDV virions and thus conclude that it is not a structural virion component.
has issue date	2001-04-30(xsd:dateTime)
bibo:doi	10.1016/s0168-1702(00)00247-1
bibo:pmid	11226573
has license	els-covid
sha1sum (hex)	0d876c35466d6ebea16d2aae89d3216afadf7457
schema:url	https://doi.org/10.1016/s0168-1702%2800%2900247-1
resource representing a document's title	An ORF-2a protein is not present at a significant level in virions of the arterivirus lactate dehydrogenase-elevating virus
has PubMed Central identifier	PMC7127614
has PubMed identifier	11226573
schema:publication	Virus Research
resource representing a document's body	covid:0d876c35466d6ebea16d2aae89d3216afadf7457#body_text
is schema:about of	named entity 'PROTEIN ' named entity 'glycoprotein' named entity 'infected' named entity 'proteins' named entity 'level' »more»

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