About: A Simulated Single Ventilator / Dual Patient Ventilation Strategy for Acute Respiratory Distress Syndrome During the COVID-19 Pandemic

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About: A Simulated Single Ventilator / Dual Patient Ventilation Strategy for Acute Respiratory Distress Syndrome During the COVID-19 Pandemic Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	A Simulated Single Ventilator / Dual Patient Ventilation Strategy for Acute Respiratory Distress Syndrome During the COVID-19 Pandemic
Creator	Williams, Steven Costar, Edward Doorly, Denis Kennedy, Caroline Kerrigan, Eric »more»
source	MedRxiv
abstract	The potential for acute shortages of ventilators at the peak of Covid-19 pandemic has raised the possibility of needing to support two patients from a single ventilator. To provide a system for understanding and prototyping designs we have developed a mathematical model of two patients supported by a mechanical ventilator. We propose a standard setup where we simulate the introduction of T-splitters to supply air to two patients and a modified setup where we introduce a variable resistance in each inhalation pathway and one-way valves in each exhalation pathway. Using the standard setup, we demonstrate that ventilating two patients with mismatched lung compliances from a single ventilator will lead to clinically-significant reductions in tidal volume in the patient with the lowest respiratory compliance. Using the modified setup, we demonstrate that it is possible to achieve the same tidal volumes in two patients with mismatched lung compliances, and we show that the tidal volume of one patient can be manipulated independently of the other. The results indicate that, with appropriate modifications, two patients could be supported from a single ventilator with independent control of tidal volumes.
has issue date	2020-04-07(xsd:dateTime)
bibo:doi	10.1101/2020.04.07.20056309
has license	medrxiv
sha1sum (hex)	0d106ec3dd1cc5a9d90ed7f7fe04c1797492935f
schema:url	https://doi.org/10.1101/2020.04.07.20056309
resource representing a document's title	A Simulated Single Ventilator / Dual Patient Ventilation Strategy for Acute Respiratory Distress Syndrome During the COVID-19 Pandemic
resource representing a document's body	covid:0d106ec3dd1cc5a9d90ed7f7fe04c1797492935f#body_text
is schema:about of	named entity 'simulate' named entity 'patient' named entity 'peak' named entity 'Patient' named entity 'patients' »more»

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